Searchable abstracts of presentations at key conferences in endocrinology

ea0016p510 | Obesity | ECE2008

Daily and nightly urinary free cortisol ratio as a marker of the hypothalamic-pituitary-adrenal (HPA) axis activity in abdominal obesity

Agostinio Romina Di , Vicennati Valentina , Pagotto Uberto , Genghini Silvia , Ambrosi Bruno , Maccario Mauro , Uberti Ettore Degli , Boscaro Marco , Cavagnini Francesco , Mantero Franco , Armanini Decio , Vettor Roberto , Marugo Mario , Pasquali Renato

Abdominal obesity (AO) might have a hyperactivation of the HPA axis but previous studies are limited by the small and heterogeneous number of patients investigated. The aim of this study was to evaluate urinary free cortisol (UFC) output during daily and nightly hours in a large cohort of AO women versus normal weight controls (CT). 107 AO women and 37 CT women were enrolled in this study; all subjects underwent a complete physical examination, an OGTT and biochemical determin...